User profiles for Sebastian Levesque

Sébastien A. Lévesque

- Verified email at crulrg.ulaval.ca - Cited by 2741

Sebastien Levesque

- Verified email at usherbrooke.ca - Cited by 1130

Sébastien Levesque

- Verified email at childrens.harvard.edu - Cited by 287

Impact of COVID-19 pandemic on mechanical reperfusion for patients with STEMI

…, G Gabrielli, XF Rios, N Bakraceski, S Levesque… - Journal of the American …, 2020 - jacc.org
Background The fear of contagion during the coronavirus disease-2019 (COVID-19) pandemic
may have potentially refrained patients with ST-segment elevation myocardial infarction (…

Mechanisms of stent thrombosis analysed by optical coherence tomography: insights from the national PESTO French registry

…, T Lhermusier, A Mulliez, S Levesque… - European heart …, 2016 - academic.oup.com
Aims Angiography has limited value for identifying the causes of stent thrombosis (ST). We
studied a large cohort of patients by optical coherence tomography (OCT) to explore ST …

Neutrophils mediate blood–spinal cord barrier disruption in demyelinating neuroinflammatory diseases

B Aubé, SA Lévesque, A Paré, É Chamma… - The Journal of …, 2014 - journals.aai.org
Disruption of the blood–brain and blood–spinal cord barriers (BBB and BSCB, respectively)
and immune cell infiltration are early pathophysiological hallmarks of multiple sclerosis (MS)…

Impact of ectoenzymes on p2 and p1 receptor signaling

F Kukulski, SA Lévesque, J Sévigny - Advances in pharmacology, 2011 - Elsevier
P2 receptors that are activated by extracellular nucleotides (eg, ATP, ADP, UTP, UDP, Ap n
A) and P1 receptors activated by adenosine control a diversity of biological processes. The …

Myeloid cell transmigration across the CNS vasculature triggers IL-1β–driven neuroinflammation during autoimmune encephalomyelitis in mice

SA Lévesque, A Paré, B Mailhot… - Journal of Experimental …, 2016 - rupress.org
Growing evidence supports a role for IL-1 in multiple sclerosis and experimental autoimmune
encephalomyelitis (EAE), but how it impacts neuroinflammation is poorly understood. We …

[HTML][HTML] The phenotypic spectrum of Schaaf-Yang syndrome: 18 new affected individuals from 14 families

…, IB Mathijssen, S Levesque… - Genetics in …, 2017 - nature.com
Purpose: Truncating mutations in the maternally imprinted, paternally expressed gene
MAGEL2, which is located in the Prader-Willi critical region 15q11–13, have recently been …

NTPDase1 governs P2X7‐dependent functions in murine macrophages

SA Lévesque, F Kukulski, K Enjyoji… - European journal of …, 2010 - Wiley Online Library
P2X 7 receptor is an adenosine triphosphate (ATP)‐gated ion channel within the multiprotein
inflammasome complex. Until now, little is known about regulation of P2X 7 effector …

[HTML][HTML] Central canal ependymal cells proliferate extensively in response to traumatic spinal cord injury but not demyelinating lesions

…, S Beaudoin, C Breault-Dugas, I Pineau, SA Levesque… - PloS one, 2014 - journals.plos.org
The adult mammalian spinal cord has limited regenerative capacity in settings such as
spinal cord injury (SCI) and multiple sclerosis (MS). Recent studies have revealed that …

Phages as friends and enemies in food processing

AG de Melo, S Levesque, S Moineau - Current opinion in biotechnology, 2018 - Elsevier
Highlights • Phages can be detrimental to food fermentations. • Several antiphage control
strategies are available. • Phages can be used to control foodborne pathogens. • Development …

Cloning and Characterization of Mouse Nucleoside Triphosphate Diphosphohydrolase-8,

F Bigonnesse, SA Lévesque, F Kukulski, J Lecka… - Biochemistry, 2004 - ACS Publications
A novel mammalian plasma membrane bound nucleoside triphosphate diphosphohydrolase
(NTPDase), named NTPDase8, has been cloned and characterized. Analysis of cDNA …