Mycobacterium tuberculosis upregulates microglial matrix metalloproteinase-1 and-3 expression and secretion via NF-κB–and activator protein-1–dependent …
…, CJ Pennington, F Roncaroli, S Dholakia… - The Journal of …, 2010 - journals.aai.org
Inflammatory tissue destruction is central to pathology in CNS tuberculosis (TB). We
hypothesized that microglial-derived matrix metalloproteinases (MMPs) have a key role in driving …
hypothesized that microglial-derived matrix metalloproteinases (MMPs) have a key role in driving …
The association of noise and surgical-site infection in day-case hernia repairs
S Dholakia, JP Jeans, U Khalid, S Dholakia, C D'Souza… - Surgery, 2015 - Elsevier
Introduction Surgical-site infections (SSIs) are associated with an increased duration of
hospital stay, poorer quality of life, and an marked increase in cost to the hospital. Lapses in …
hospital stay, poorer quality of life, and an marked increase in cost to the hospital. Lapses in …
[HTML][HTML] Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα, NFκB, p38 and caspase 8 …
JA Green, S Dholakia, K Janczar, CWM Ong… - Journal Of …, 2011 - Springer
Tuberculosis (TB) of the central nervous system (CNS) is a deadly disease characterized by
extensive tissue destruction, driven by molecules such as Matrix Metalloproteinase-2 (MMP-…
extensive tissue destruction, driven by molecules such as Matrix Metalloproteinase-2 (MMP-…
Pubic lice: an endangered species?
S Dholakia, J Buckler, JP Jeans, A Pillai… - Sexually Transmitted …, 2014 - journals.lww.com
Aim To report the changing incidence of pubic lice infestation from our unit over the last 10
years and assess its association, if any, with pubic hair removal of any kind. Methods …
years and assess its association, if any, with pubic hair removal of any kind. Methods …
[HTML][HTML] In an in vitro model of human tuberculosis, monocyte-microglial networks regulate matrix metalloproteinase-1 and -3 gene expression and secretion via a …
JA Green, L Rand, R Moores, S Dholakia… - Journal of …, 2013 - Springer
Background Tuberculosis (TB) of the central nervous system (CNS) is characterized by extensive
tissue inflammation, driven by molecules that cleave extracellular matrix such as matrix …
tissue inflammation, driven by molecules that cleave extracellular matrix such as matrix …
[HTML][HTML] The WRaPT process–a novel and patient-centred approach to workforce planning by a clinically active workforce
S Kanagaratnam, S Dholakia, J Wood… - Future Healthcare …, 2019 - ncbi.nlm.nih.gov
The concept of supply and demand is well established within the health economy of the UK.
However, complex health and social care needs, associated with an ageing population, …
However, complex health and social care needs, associated with an ageing population, …
Evaluation of a Trauma Pathway Within an Increasing Access to Psychological Therapies (IAPT) Service
…, A Beasley, TK Ting, H Collier, S Dholakia… - BJPsych Open, 2022 - cambridge.org
AimsThe Enhanced Trauma Pathway (ETP) at Berkshire Healthcare NHS Foundation Trust
was established in 2018 to manage high demand on a highly specialist psychology team …
was established in 2018 to manage high demand on a highly specialist psychology team …
[HTML][HTML] The clinically led worforcE and activity redesign (CLEAR) programme: a novel data-driven healthcare improvement methodology
EJ Corner, M Camilleri, S Dholakia, C Gredal… - BMC Health Services …, 2022 - Springer
Background The NHS is facing substantial pressures to recover from the COVID-19 pandemic.
Optimising workforce modelling is a fundamental component of the recovery plan. The …
Optimising workforce modelling is a fundamental component of the recovery plan. The …
[PDF][PDF] This information is current as Networks
…, JC Porter, D Agranoff, DRF Roncaroli, S Dholakia… - academia.edu
Inflammatory tissue destruction is central to pathology in CNS tuberculosis (TB). We
hypothesized that microglial-derived matrix metalloproteinases (MMPs) have a key role in driving …
hypothesized that microglial-derived matrix metalloproteinases (MMPs) have a key role in driving …
Matrix metalloproteinase driven tissue destruction in central nervous system tuberculosis is regulated by NFκB
J Green, S Dholakia, R Moores, L Rand… - Journal of …, 2008 - journalofinfection.com
Introduction: Involvement of the central nervous system (CNS) is the most serious
manifestation of extra pulmonary tuberculosis (TB). Matrix metalloproteinases (MMPs) are up-…
manifestation of extra pulmonary tuberculosis (TB). Matrix metalloproteinases (MMPs) are up-…