Ischaemia-reperfusion injury occurs when the blood supply to an organ is disrupted and then
restored, and underlies many disorders, notably heart attack and stroke. While reperfusion …

Background Other than glycemic control, there are no treatments for diabetic neuropathy.
Thus, identifying potentially modifiable risk factors for neuropathy is crucial. We studied risk …

Mitochondrial β‐oxidation is a complex pathway involving, in the case of saturated straight
chain fatty acids of even carbon number, at least 16 proteins which are organized into two …

The enzymic stages of mammalian mitochondrial β-oxidation were elucidated some 30–40
years ago. However, the discovery of a membrane-associated multifunctional enzyme of β-…

The differentiation of IL-10-producing regulatory B cells (Bregs) in response to gut-microbiota-derived
signals supports the maintenance of tolerance. However, whether microbiota-…

The control of mitochondrial β-oxidation, including the delivery of acyl moieties from the
plasma membrane to the mitochondrion, is reviewed. Control of β-oxidation flux appears to be …

High-fat, low-carbohydrate diets, known as ketogenic diets, have been used as a non-pharmacological
treatment for refractory epilepsy. A key mechanism of this treatment is thought to …

Objectives: (1) To characterise neurodevelopmental outcome of neonates with necrotizing
enterocolitis (NEC); (2) to define whether NEC increases risk of neurodevelopmental …

A female infant of nonconsanguineous Indian parents presented at 4 months with a
hypoglycemic convulsion. Further episodes of hypoketotic hypoglycemia were associated with …

Objective: The aim of this study was to evaluate the feasibility and safety of nonoperative
treatment of acute nonperforated appendicitis with antibiotics in children. Methods: A pilot …