Opioid abuse has increased in the last decade, primarily as a result of increased access to
prescription opioids. Physicians are also increasingly administering opioid analgesics for …

Background Hair cortisol analysis is increasingly being appreciated and applied in both
research and medicine, aiding endocrinologists with diagnosis. Content We provide an …

Purpose Current methods for measuring long-term endogenous production of cortisol can
be challenging due to the need to take multiple urine, saliva or serum samples. Hair grows …

In a collaborative multicenter case-control study, we investigated the effect of factor V Leiden
mutation, prothrombin gene mutation, and inherited deficiencies of protein C, protein S, and …

Objective: Deep vein thrombosis (DVT) is a multifactorial disease. Recently, inflammation
has been suggested as a risk factor for DVT. The question is whether inflammation is a cause …

In a direct assay comparison we evaluated the diagnostic performance of 10 novel D-Dimer
assays for the exclusion of deep venous thrombosis (DVT). In addition, 3 conventional …

Background: Hair cortisol analysis has been shown to be an effective measure of chronic
stress. Cortisol is assumed to incorporate into hair via serum, sebum, and sweat sources; …

The two 11β-hydroxysteroid dehydrogenase (11β-HSD) isozymes catalyze the interconversion
of cortisol and cortisone. Type 1 11β-HSD (11β-HSD1) has bidirectional activity, while …

Context: Chromogranin A (CgA) is used as a generic tumor marker for neuroendocrine tumors.
Proton pump inhibitors (PPI) are known to increase CgA, but it is not clear to what extent, …

This study aimed to examine the effects of sex (males vs. females) and sex hormones (menstrual
cycle phases in women) on sympathetic responsiveness to severe chemoreflex …