Systematic review with meta‐analysis: volatile organic compound analysis to improve faecal immunochemical testing in the detection of colorectal cancer

S Chandrapalan, S Bosch, J Cubiella… - Alimentary …, 2021 - Wiley Online Library
Background Faecal immunochemical test (FIT) is emerging as a valid test to rule‐out the
presence of colorectal cancer (CRC). However, the accuracy of FIT is dependent on the cut‐off …

Urine as a biological modality for colorectal cancer detection

S Chandrapalan, RP Arasaradnam - Expert review of molecular …, 2020 - Taylor & Francis
Introduction: The increasing incidence of colorectal cancer (CRC) in young adults warrants
early and preferably noninvasive diagnostic modalities. Although the current stool-based …

[HTML][HTML] A Systematic Review and Meta-Analysis: Volatile Organic Compound Analysis in the Detection of Hepatobiliary and Pancreatic Cancers

M Pelling, S Chandrapalan, E West, RP Arasaradnam - Cancers, 2023 - mdpi.com
Simple Summary Hepatobiliary cancers are notoriously difficult to detect, frequently leading
to diagnosis in later stages of disease when curative treatment is not an option. The currently …

[HTML][HTML] C-reactive protein and albumin association with mortality of hospitalised SARS-CoV-2 patients: A tertiary hospital experience

…, M Tabuso, A Farrugia, S Chandrapalan… - Clinical …, 2020 - ncbi.nlm.nih.gov
Objective The objective was to study hospitalised COVID-19 patients’ mortality and
intensive care unit (ICU) admission with covariates of interest (age, gender, ethnicity, clinical …

[HTML][HTML] Exploring how microbiome signatures change across inflammatory bowel disease conditions and disease locations

…, A Logan, R Iriarte, A Bannaga, S Chandrapalan… - Scientific Reports, 2021 - nature.com
Understanding the variables that influence microbiome studies is critical for successful
translational research. Inflammatory bowel disease (IBD) is a complex group of diseases that can …

Implementation of a care bundle improves the management of patients with non-alcoholic fatty liver disease

…, PS Lee, T Hardy, D Beaton, S Chandrapalan… - Frontline …, 2021 - fg.bmj.com
Background Non-alcoholic fatty liver disease (NAFLD) is common and is associated with
liver-related and cardiovascular-related morbidity. Our aims were: (1) to review the current …

Breath diagnostics in the era of SARS-CoV-2—clinical and research arena

S Chandrapalan, K Persaud… - Journal of Breath …, 2020 - iopscience.iop.org
The emergence of the SARS-CoV-2 pandemic has transformed not just healthcare, but also
economic systems on a global scale. Despite significant efforts to contain the infection, it …

[PDF][PDF] Influence of seasonal and operator variations on diagnostic accuracy of lateral flow devices during the COVID-19 pandemic: a systematic review and meta …

A Krishnamoorthy, S Chandrapalan… - Clinical …, 2023 - rcpjournals.org
Background Lateral flow tests (LFT) are point-of-care rapid antigen tests that allow isolation
and control of disease outbreaks through convenient, practical testing. However, studies …

[HTML][HTML] The Influence of Mechanical Bowel Preparation on Volatile Organic Compounds for the Detection of Gastrointestinal Disease—A Systematic Review

A Krishnamoorthy, S Chandrapalan, S Bosch… - Sensors, 2023 - mdpi.com
(1) Background: Colorectal cancer is the second commonest cause of cancer deaths
worldwide; recently, volatile organic compounds (VOCs) have been proposed as potential …

Performance of the faecal immunochemical test for the detection of colorectal neoplasms and the role of proton pump inhibitors in their diagnostic accuracy

S Chandrapalan, SW Hee, MM Widlak… - Colorectal …, 2021 - Wiley Online Library
Aim The faecal immunochemical test (FIT) is currently utilized in both symptomatic and
screening populations, but little is known about factors that affect its performance. For example, …