Links between sleep and depression are strong. About three quarters of depressed patients
have insomnia symptoms, and hypersomnia is present in about 40% of young depressed …

Background Helicobacter pylori (H pylori) is the main cause of peptic ulcer disease. The
role of H pylori in non‐ulcer dyspepsia is less clear. Objectives To determine the effect of H …

<p>This review is an abridged version of a Cochrane Review previously published in the
Cochrane Database of Systematic Reviews 2010, Issue 4, Art. No.: MR000013 DOI: 10.1002/…

Most antidepressants change sleep; in particular, they alter the physiological patterns of sleep
stages recorded overnight with EEG and other physiological measures. These effects are …

Background: Irritable bowel syndrome (IBS) is a common health problem affecting a substantial
proportion of the population. Many individuals with symptoms of IBS do not seek medical …

Background Poor recruitment to randomised controlled trials (RCTs) is a widespread problem.
Provision of interventions aimed at supporting or incentivising clinicians may improve …

Background Healthcare workers (HCWs) will play a key role in any response to pandemic
influenza, and the UK healthcare system's ability to cope during an influenza pandemic will …

Background: Widespread use of automated sensitive assays for thyroid hormones and
thyroid-stimulating hormone (TSH) has increased identification of mild thyroid dysfunction, …

Over the last decade there have been further developments in our knowledge of the risks
and benefits of benzodiazepines, and of the risks and benefits of alternatives to …

Background Previous studies have suggested that minor changes in thyroid function are
associated with risk of atrial fibrillation (AF). Our objective was to determine the relationship …