The cardiovascular actions of the magnesium ion at pharmacological concentrations
include coronary and systemic vasodilatation, platelet inhibition, and antiarrhythmic effects. …

Protein-truncating mutations in the dystrophin gene lead to the most common childhood form
of muscle wasting, Duchenne muscular dystrophy. Becker muscular dystrophy, a condition …

Manipulation of pre-mRNA splicing by antisense oligonucleotides (AOs) offers considerable
potential for a number of genetic disorders. One of these is Duchenne muscular dystrophy (…

The mdx mouse model of muscular dystrophy arose due to a nonsense mutation in exon 23
of the dystrophin gene. We have previously demonstrated that 2′- O -methyl …

Background Duchenne and Becker muscular dystrophies are allelic disorders arising from
mutations in the dystrophin gene. Duchenne muscular dystrophy is characterised by an …

Root architecture traits in wheat are important in deep soil moisture acquisition and may be
used to improve adaptation to water-limited environments. The genetic architecture of two …

Background Water availability is a major limiting factor for wheat (Triticum aestivum L.)
production in rain-fed agricultural systems worldwide. Root system architecture has important …

Objective: To examine the association between long‐term health conditions and being out
of the labour force among older Australians. Design, setting and participants: Retrospective …

The second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2) examined the effect
of an intravenous regimen of magnesium sulphate in 2316 patients with suspected acute …

A stay-green phenotype enables crops to retain green leaves longer after anthesis compared
with senescent types, potentially improving yield. Measuring the normalized difference …