Health status and quality of life measures are widely used in the clinical assessment of
rheumatoid and other forms of arthritis. A range of measures is available, mainly as self-…

Objective To investigate the safety and efficacy of MRA, a recombinant human anti–interleukin‐6
(anti–IL‐6) receptor monoclonal antibody of the IgG1 subclass that inhibits the function …

Objective The inflammatory arthritides (IAs) make up a significant proportion of conditions
followed up in rheumatology clinics. These patients require regular monitoring, but this is …

The observation that circulating leucocytes adhere to and migrate across the vascular
endothelium was first made 70yr ago; this was noted to occur without breach of the endothelial …

… IL-17 T cells and other cytokineexpressing T cells (CD4 versus CD4 T cells) in the peripheral
blood (PB) and synovial fluid (SF) of patients with PsA. Our findings show that IL-17CD4 T …

Objective To investigate whether antidrug antibodies and/or drug non‐trough levels predict
the long‐term treatment response in a large cohort of patients with rheumatoid arthritis (RA) …

… In RA, therapeutic activity has been linked to modulation of antigen-processing activity,
including inhibition of T-cell activation and cytokine release (46, 47); increasing evidence of …

Objective. To investigate predictors of flare in rheumatoid arthritis (RA) patients with low disease
activity (LDA) and to evaluate the effect of flare on 12-month clinical outcomes. Methods. …

… All clinicians described rapid redesign of their respective services: ‘We had to do it due to
a crisis, we hadn’t really planned and prepared to do it properly’ (physiotherapist) and ‘All the …

… Gadolinium-enhanced 1.5/3.0 T MRI of the signal knee will be performed at baseline and
six months according to the protocol outlined in Table 3. All images will be quality controlled by …