Crohn's disease ( CD ) is a complex and highly heterogeneous chronic inflammatory
disorder, primarily affecting the gastrointestinal tract. Genetic and functional studies have …

Crohn's disease (CD) is associated with delayed neutrophil recruitment and bacterial
clearance at sites of acute inflammation as a result of impaired secretion of proinflammatory …

Background and Aims: ADAM [A Disintegrin And Metalloproteinase] is a family of peptidase
proteins which have diverse roles in tissue homeostasis and immunity. Here, we study ADAM…

An 85-year-old man was referred for assessment of recurrent iron deficient anemia. Upper
and lower endoscopy showed no significant pathology as a cause for his anemia, and …

Background Infliximab dose escalation (DE) can be used in inflammatory bowel disease
patient; however, the long-term benefit remains unclear, especially in those with antibodies to …

Objective. Giardia lamblia is the most common enteric protozoan world-wide. The prevalence
varies internationally. Patients with giardiasis typically have diarrhoea but may have …

Aims The aims of this retrospective study were to identify markers predictive of increased
mortality in patients having a PEG for the first time, and to assess if use of sedation with …

Introduction Tofacitinib is a pan-Janus Kinase inhibitor which is effective for induction and
maintenance of remission in moderate to severely active ulcerative colitis (UC). The safety and …

Background Antibodies to infliximab (ATI) can complicate infliximab (IFX) treatment of
inflammatory bowel disease (IBD) patients. Aims To identify a clinically relevant threshold for ATI …

Question: A 64-year-old man was admitted with a 1-week history of confusion. Computed
tomography of the brain revealed bilateral frontoparietal infarcts and he was treated with aspirin…