Reflection & Reaction

TJ Littlewood, D Cella, JW Nortier - J Clin Oncol, 2001 - thelancet.com
Timothy J Littlewood, David Cella, and Johan WR Nortier … 2 Littlewood TJ, Bajetta E,
Nortier JWR, et al. for the Epoetin Alfa Study Group. Effects of epoetin alfa on hematologic …

Efficacy and safety of darbepoetin alfa in anaemic patients with lymphoproliferative malignancies: a randomized, double‐blind, placebo‐controlled study

…, J Matcham, G Rossi, TJ Littlewood - British journal of …, 2003 - Wiley Online Library
This phase 3, randomized, double‐blind, placebo‐controlled study was designed to evaluate
the efficacy and safety of darbepoetin alfa in anaemic patients with lymphoproliferative …

[HTML][HTML] The Role of the Iron Transporter ABCB7 in Refractory Anemia with Ring Sideroblasts

…, B Pushkaran, C Fidler, H Cattan, TJ Littlewood… - PloS one, 2008 - journals.plos.org
Refractory Anemia with Ring Sideroblasts (RARS) is an acquired myelodysplastic syndrome
(MDS) characterized by an excess iron accumulation in the mitochondria of erythroblasts. …

NCRI phase II study of CHOP in combination with ofatumumab in induction and maintenance in newly diagnosed Richter syndrome

…, TJ Littlewood, H McCarthy, J Murray… - British journal of …, 2016 - Wiley Online Library
Richter syndrome ( RS ) is associated with chemotherapy resistance and a poor historical
median overall survival ( OS ) of 8–10 months. We conducted a phase II trial of standard …

The impact of hemoglobin levels on treatment outcomes in patients with cancer

TJ Littlewood - Seminars in oncology, 2001 - Elsevier
Clinical trials and surveys have shown that a majority of patients with cancer have low
hemoglobin levels as a result of the disease and/or treatment. Clinical trials also have shown that …

Improving the immediate management of neutropenic sepsis in the UK: lessons from a national audit

…, J Warnick, K Stretton, TJ Littlewood - British journal of …, 2011 - Wiley Online Library
Recent disquiet at inadequacies in the immediate management of neutropenic sepsis in the
UK led to a new, gold standard ‘door‐to‐needle’ time of 1 h for the administration of …

G‐CSF after peripheral blood stem cell transplantation in lymphoma patients significantly accelerated neutrophil recovery and shortened time in hospital: results of a …

…, SM Kelsey, SA Johnson, TJ Littlewood… - British journal of …, 1997 - Wiley Online Library
We have undertaken a prospective randomized study in 90 patients with relapsed or resistant
lymphomas to assess the value of G‐CSF (lenograstim) in the acceleration of myeloid …

[HTML][HTML] Resolving difficult phylogenetic questions: why more sequences are not enough

…, H Brinkmann, DV Lavrov, DTJ Littlewood… - PLoS …, 2011 - journals.plos.org
In the quest to reconstruct the Tree of Life, researchers have increasingly turned to
phylogenomics, the inference of phylogenetic relationships using genome-scale data (Box 1). …

Interrelationships and evolution of the tapeworms (Platyhelminthes: Cestoda)

…, DTJ Littlewood, RA Bray, J Mariaux - Molecular Phylogenetics …, 2001 - Elsevier
Interrelationships of the tapeworms (Platyhelminthes: Cestoda) were examined by use of small
(SSU) and large (LSU) subunit ribosomal DNA sequences and morphological characters. …

The signs, symptoms and help-seeking experiences of neutropenic sepsis patients before they reach hospital: A qualitative study

RT Clarke, S Bird, I Kakuchi, TJ Littlewood… - Supportive Care in …, 2015 - Springer
Purpose Neutropenic sepsis (NS) is a medical emergency in which urgent treatment with
antibiotics is known to improve outcomes, yet there are minimal data about what happens to …