[HTML][HTML] Clinical features and management of human monkeypox: a retrospective observational study in the UK
…, S Aston, R Ball, NJ Beeching, TJ Blanchard… - The Lancet Infectious …, 2022 - thelancet.com
Background Cases of human monkeypox are rarely seen outside of west and central Africa.
There are few data regarding viral kinetics or the duration of viral shedding and no licensed …
There are few data regarding viral kinetics or the duration of viral shedding and no licensed …
Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara
Immunization with irradiated sporozoites can protect against malaria infection and intensive
efforts are aimed at reproducing this effect with subunit vaccines. A particular sequence of …
efforts are aimed at reproducing this effect with subunit vaccines. A particular sequence of …
[HTML][HTML] Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans
…, S Dunachie, G Butcher, JM Vuola, TJ Blanchard… - Nature medicine, 2003 - nature.com
In animals, effective immune responses against malignancies and against several infectious
pathogens, including malaria, are mediated by T cells. Here we show that a heterologous …
pathogens, including malaria, are mediated by T cells. Here we show that a heterologous …
Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: implications for use as a human vaccine.
TJ Blanchard, A Alcami, P Andrea… - The Journal of …, 1998 - microbiologyresearch.org
Modified virus Ankara (MVA) is a vaccinia virus (VV) strain that was attenuated by serial
passage through chick embryo fibroblasts (CEFs) and contains six large genomic deletions …
passage through chick embryo fibroblasts (CEFs) and contains six large genomic deletions …
Effective induction of simian immunodeficiency virus-specific cytotoxic T lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia …
T Hanke, RV Samuel, TJ Blanchard… - Journal of …, 1999 - Am Soc Microbiol
DNA and modified vaccinia virus Ankara (MVA) are vaccine vehicles suitable and safe for
use in humans. Here, by using a multicytotoxic T-lymphocyte (CTL) epitope gene and a DNA …
use in humans. Here, by using a multicytotoxic T-lymphocyte (CTL) epitope gene and a DNA …
[HTML][HTML] Pneumocystis pneumonia, a COVID-19 mimic, reminds us of the importance of HIV testing in COVID-19
While clinical environments are highly focused on COVID-19, reports of missed or delayed
treatment for conditions that imitate COVID-19, such as pneumonia caused by the fungus …
treatment for conditions that imitate COVID-19, such as pneumonia caused by the fungus …
A prime-boost immunisation regimen using DNA followed by recombinant modified vaccinia virus Ankara induces strong cellular immune responses against the …
…, JAM Langermans, SC Gilbert, TJ Blanchard… - Vaccine, 2001 - Elsevier
Two chimpanzees were vaccinated intramuscularly against malaria using plasmid DNA
expressing the pre-erythrocytic antigens thrombospondin related adhesion protein (PfTRAP) …
expressing the pre-erythrocytic antigens thrombospondin related adhesion protein (PfTRAP) …
[PDF][PDF] Chronic norovirus infection in an HIV-positive patient with persistent diarrhoea: a novel cause
…, P Klapper, M Guiver, TJ Blanchard - Journal of Clinical …, 2010 - researchgate.net
We describe the first recorded case of chronic norovirus infection in a patient with HIV. Our
patient had poor compliance with antiretroviral therapy and subsequent profound …
patient had poor compliance with antiretroviral therapy and subsequent profound …
Effective induction of HIV-specific CTL by multi-epitope using gene gun in a combined vaccination regime
Reliable and effective induction of cytotoxic T-lymphocytes (CTL) is one of the prime objectives
of vaccine research. Previously, novel HIV vaccine candidates were constructed as a …
of vaccine research. Previously, novel HIV vaccine candidates were constructed as a …
[HTML][HTML] Hyperinflammation with COVID-19: The key to patient deterioration?
K Haigh, ZJ Syrimi, S Irvine, TJ Blanchard… - Clinical infection in …, 2020 - Elsevier
Background The potential risk of cytokine storm in patients with coronavirus disease 2019 (COVID-19)
has been described [1]; we write to share our experience treating a 17-year-old …
has been described [1]; we write to share our experience treating a 17-year-old …