Psoriasis and atopic dermatitis are chronic and relapsing inflammatory diseases of the skin
associated with various immunologic abnormalities. Approximately 30% of psoriasis patients …

Atopic dermatitis (AD) is a chronic itching (pruritic) skin disease. It results from a complex
interplay between strong genetic and environmental factors. Genome screens of families with …

Molecular techniques have revolutionized the practice of standard microbiology. In particular,
16S rRNA sequencing, whole microbial genome sequencing and metagenomics are …

Background Susceptibility to asthma is influenced by genes and environment; implicated
genes may indicate pathways for therapeutic intervention. Genetic risk factors may be useful in …

Background Children who grow up in environments that afford them a wide range of microbial
exposures, such as traditional farms, are protected from childhood asthma and atopy. In …

ASTHMA now affects one child in seven in the United Kingdom 1 . Most cases (95%) of
childhood asthma are associated with atopy, the immunoglobulin E (IgE)-mediated familial …

Atopic dermatitis (AD) and asthma are characterized by IgE-mediated atopic (allergic) responses
to common proteins (allergens), many of which are proteinases. Loci influencing atopy …

We have carried out a genome screen for atopic dermatitis (AD) and have identified linkage
to AD on chromosomes 1q21, 17q25 and 20p. These regions correspond closely with …

Asthma is a common disease in children and young adults. Four separate reports have linked
asthma and related phenotypes to an ill-defined interval between 2q14 and 2q32 (refs. 1 – …

Atopic or immunoglobulin E (IgE)-mediated diseases include the common disorders of asthma,
atopic dermatitis and allergic rhinitis 1 . Chromosome 13q14 shows consistent linkage to …