Evidence based medicine, whose philosophical origins extend back to mid-19th century
Paris and earlier, remains a hot topic for clinicians, public health practitioners, purchasers, …

Overall rating: Excellent Strengths: Clear, conversational style; simple explanations.
Weaknesses: None Audience: Practitioners at any stage, including clinical clerks This book is …

Doctors within the NHS are confronting major changes at work. While we endeavour to improve
the quality of health care, junior doctors' hours have been reduced and the emphasis on …

Background In phase 2 trials, treatment with the combination of the nucleotide polymerase
inhibitor sofosbuvir and the NS5A inhibitor velpatasvir resulted in high rates of sustained …

Background & Aims: Histologic examination of a liver biopsy specimen is regarded as the
reference standard for detecting liver fibrosis. Biopsy can be painful and hazardous, and …

Natural killer (NK) cells provide a central defense against viral infection by using inhibitory
and activation receptors for major histocompatibility complex class I molecules as a means of …

Doctors always seek to base their decisions on the best available evidence. Often this
evidence represents extrapolations of pathophysiological principles and logic rather than …

Study Design. The biomechanical behavior of a single lumbar vertebral body after various
surgical treatments with acrylic vertebroplasty was parametrically studied using finite-element …

The detection of fibrosis within nonalcoholic fatty liver disease (NAFLD) is important for
ascertaining prognosis and the stratification of patients for emerging therapeutic intervention. We …

The British Society of Gastroenterology guidelines on the management of cholangiocarcinoma
were originally published in 2002. This is the first update since then and is based on a …