Asthma is a complex respiratory disorder characterized by marked heterogeneity in
individual patient disease triggers and response to therapy. Several asthma phenotypes …

Blood eosinophilia and tissue eosinophilia are characteristic features of allergic
inflammation and asthma, conditions associated with prominent production of TH2 cytokines …

Background In phase 2 trials, lebrikizumab, an anti-interleukin-13 monoclonal antibody,
reduced exacerbation rates and improved FEV 1 in patients with uncontrolled asthma …

Quercetin is a plant-derived flavonoid widely known by its anti-oxidant and anti-inflammatory
properties, but its oral bioavailability is very poor and this becomes difficult to assess its …

Asthma is characterized by airway inflammation rich in eosinophils. Airway eosinophilia is
associated with exacerbations and has been suggested to play a role in airway remodelling …

Background and purpose: α‐Humulene and trans‐caryophyllene are plant sesquiterpenes
with pronounced anti‐inflammatory properties. Here, we evaluated the effects of these …

Eosinophils are well known to contribute significantly to Th2 immunity, such as allergic
inflammations. Although basophils have often not been considered in the pathogenicity of …

Eosinophilic inflammation is a characteristic feature of asthma. Integrins are highly versatile
cellular receptors that regulate extravasation of eosinophils from the postcapillary segment …

Asthma is a chronic and sometimes fatal disease, which affects people of all ages
throughout the world. Important hallmarks of asthma are airway inflammation and …

Allergic inflammation involves the mobilization and trafficking of eosinophils to sites of
inflammation. Galectin-3 (Gal-3) has been shown to play a critical role in eosinophil …