One of the leading causes of morbidity and premature mortality in older people is frailty.
Frailty occurs when multiple physiological systems decline, to the extent that an individual's …

Frailty is the most problematic expression of population ageing. It is a state of vulnerability to
poor resolution of homoeostasis after a stressor event and is a consequence of cumulative …

Objective The purpose of this study was to quantify the predictive value of frailty index on 30-
day Clavien class IV (requiring critical care support) and class V (30-day mortality) …

Importance Functional status and physiologic deficits independent of age are being
recognized for surgical risk stratification. Frailty is expressed as a combination of decreased …

This paper provides a survey of the changing concepts of the etiology of epilepsy from 1860
to 2010, focusing on the first two 50‐year periods and outlining more briefly major …

Background Head and neck extirpations requiring reconstruction are challenging surgeries
with high postoperative complication risk. Methods Regional and free flap reconstructions of …

The mainstream approach to psychopathological phenotypes is focussed on easy-to-assess
operationalizable symptoms. Thinness of phenotypes and simplification of clinical constructs …

Aim Frailty and sarcopenia affect the prognosis and quality of life of patients with chronic
obstructive pulmonary disease (COPD). However, it remains uncertain which model is the …

This article describes the judgements used to interpret evidence in evidence-based
medicine (EBM) and health technology assessment (HTA). It outlines the methods and …

Objective Our objective was to examine the association of the modified frailty index (mFI)
and non-home discharge in patients undergoing surgery for endometrial cancer (EMCA) …