Alcohol use disorders

JP Connor, PS Haber, WD Hall - The Lancet, 2016 - thelancet.com
Alcohol use disorders are common in developed countries, where alcohol is cheap, readily
available, and heavily promoted. Common, mild disorders often remit in young adulthood …

An inpatient treatment and discharge planning protocol for alcohol dependence: efficacy in reducing 30-day readmissions and emergency department visits

J Wei, T Defries, M Lozada, N Young, W Huen… - Journal of general …, 2015 - Springer
ABSTRACT BACKGROUND Alcohol dependence results in multiple hospital readmissions,
but no discharge planning protocol has been studied to improve outcomes. The inpatient …

The correlation between CYP2D6 isoenzyme activity and haloperidol efficacy and safety profile in patients with alcohol addiction during the exacerbation of the …

DA Sychev, MS Zastrozhin, VV Smirnov… - Pharmacogenomics …, 2016 - Taylor & Francis
Background Today, it is proved that isoenzymes CYP2D6 and CYP3A4 are involved in
metabolism of haloperidol. In our previous investigation, we found a medium correlation …

Genotyping and phenotyping of CYP2D6 and CYP3A isoenzymes in patients with alcohol use disorder: correlation with haloperidol plasma concentration

DA Sychev, MS Zastrozhin… - Drug metabolism and …, 2017 - degruyter.com
Background: Haloperidol is used for the treatment of alcohol use disorders in patients with
signs of alcohol-related psychosis. Haloperidol therapy poses a high risk of adverse drug …

Alcohol withdrawal syndrome in critically ill patients: identification, assessment, and management

LJ Sutton, A Jutel - Critical Care Nurse, 2016 - AACN
Management of alcohol withdrawal in critically ill patients is a challenge. The alcohol
consumption histories of intensive care patients are often incomplete, limiting identification …

Pharmacodynamic genetic polymorphisms affect adverse drug reactions of haloperidol in patients with alcohol-use disorder

MS Zastrozhin, VM Brodyansky… - Pharmacogenomics …, 2017 - Taylor & Francis
Background Antipsychotic action of haloperidol is due to blockade of D2 receptors in the
mesolimbic dopamine pathway, while the adverse drug reactions are associated with striatal …

The influence of CYP3A5 polymorphisms on haloperidol treatment in patients with alcohol addiction

MS Zastrozhin, EA Grishina, KA Ryzhikova… - Pharmacogenomics …, 2017 - Taylor & Francis
Background Isoenzymes CYP2D6 and CYP3A4, the activity of which varies widely, are
involved in metabolism of haloperidol and may influence its profile of efficacy and safety …

[HTML][HTML] The Substance Use Treatment and Recovery Team (START) study: protocol for a multi-site randomized controlled trial evaluating an intervention to improve …

AJ Ober, C Murray-Krezan, K Page… - Addiction Science & …, 2022 - Springer
Background People with opioid use disorder experience high burden of disease from
medical comorbidities and are increasingly hospitalized with medical complications …

Symptom-triggered therapy for assessment and management of alcohol withdrawal syndrome in the emergency department short-stay clinical decision unit

MF Ismail, K Doherty, P Bradshaw… - Emergency Medicine …, 2019 - emj.bmj.com
Introduction We previously reported that benzodiazepine detoxification for alcohol
withdrawal using symptom-triggered therapy (STT) with oral diazepam reduced length of …

[PDF][PDF] Alcohol use disorder among general hospital medical inpatients

I Danovitch, T Nuckols, KE Watkins, AJ Ober… - Addiction …, 2021 - scivisionpub.com
Objectives: We sought to examine alcohol use disorder (AUD) among general hospital
medical inpatients with respect to identification, service utilization, and initiation of …