[HTML][HTML] Human leukocyte antigen (HLA) system: genetics and association with bacterial and viral infections

S Medhasi, N Chantratita - Journal of Immunology Research, 2022 - hindawi.com
The human leukocyte antigen (HLA) system is one of the most crucial host factors
influencing disease progression in bacterial and viral infections. This review provides the …

[HTML][HTML] Personalized medicine in Europe: not yet personal enough?

A Di Paolo, F Sarkozy, B Ryll, U Siebert - BMC health services research, 2017 - Springer
Background Personalized medicine has the potential to allow patients to receive drugs
specific to their individual disease, and to increase the efficiency of the healthcare system …

Implementing individualized medicine into the medical practice

KN Lazaridis, TM MCAllister… - American Journal of …, 2014 - Wiley Online Library
There is increasing recognition that genomic medicine as part of individualized medicine
has a defined role in patient care. Rapid advances in technology and decreasing cost …

[HTML][HTML] Building towards precision medicine: empowering medical professionals for the next revolution

S McGrath, D Ghersi - BMC medical genomics, 2016 - Springer
A new paradigm in disease classification, diagnosis and treatment is rapidly approaching.
Known as precision medicine, this new healthcare model incorporates and integrates …

[HTML][HTML] The role of the complement system in age-related macular degeneration

BHF Weber, PC Issa, D Pauly, P Herrmann… - Deutsches Ärzteblatt …, 2014 - ncbi.nlm.nih.gov
Background Age-related macular degeneration (AMD) is a common retinal disease in older
people. In Europe, about 1.6% of persons over age 65 and more than 13% of persons over …

Integrating hereditary breast and ovarian cancer genetic counselling and testing into mainstream clinical practice: Legal and ethical challenges

M Charron, B Kaiser, A Dauge, H Gallois… - Critical Reviews in …, 2022 - Elsevier
Health professionals not specialized in genetics are expected to take an increasing role in
genetic services delivery. This article aims to identify legal and ethical challenges related to …

[HTML][HTML] “Balancing expectations with actual realities”: Conversations with clinicians and scientists in the first year of a high-risk childhood cancer precision medicine …

BC McGill, CE Wakefield, K Hetherington… - Journal of personalized …, 2020 - mdpi.com
Precision medicine is changing cancer care and placing new demands on oncology
professionals. Precision medicine trials for high-risk childhood cancer exemplify these …

[HTML][HTML] Current issues in medically assisted reproduction and genetics in Europe: research, clinical practice, ethics, legal issues and policy

JC Harper, J Geraedts, P Borry, MC Cornel… - European Journal of …, 2013 - nature.com
In March 2005, a group of experts from the European Society of Human Genetics and
European Society of Human Reproduction and Embryology met to discuss the interface …

The Voices of Stakeholders Involved in Precision Medicine: The Co-Design and Evaluation of Qualitative Indicators of Intervention Acceptability, Fidelity and Context …

J Smith, J Braithwaite, TA O'Brien… - Qualitative Health …, 2022 - journals.sagepub.com
We report a novel approach of amalgamating implementation outcomes of acceptability and
fidelity alongside context as a new way of qualitatively evaluating implementation outcomes …

An inter-professional approach to personalized medicine education: one institution's experience

CM Formea, WT Nicholson, CR Vitek - Personalized medicine, 2015 - Future Medicine
Personalized medicine offers the promise of better diagnoses, targeted therapies and
individualized treatment plans. Pharmacogenomics is an integral component of …