Executive summary The past six decades have seen remarkable improvements in health
outcomes for people with cystic fibrosis, which was once a fatal disease of infants and young …

The mucopolysaccharidoses are a group of inherited metabolic diseases caused by
deficiencies in enzymes involved in the sequential degradation of glycosaminoglycans …

Purpose Transition of care of adolescents with chronic conditions is a critical area for
clinicians. Patient-reported outcomes may provide important information on the quality of …

Background: Medical advances have dramatically improved the long-term prognosis of
children and adolescents with once-fatal hepatobiliary diseases. However, there is no …

The adolescent period is characterised by fundamental hormonal changes, which affect sex
steroid production, cortisol metabolism and insulin sensitivity. These physiological changes …

Background Healthcare outpatient visits have increased in recent years, and young adults
are often given as an explanatory factor for many avoidable visits. Objective The objective of …

Awareness is growing that young adults may have distinctive experiences of adult
healthcare and that their needs may differ from those of other adult users. In addition, the …

Background Improvements in care and treatment have led to more young adults with life-
limiting conditions living beyond childhood, which means they must make the transition from …

Background The numbers of children with long‐term illnesses surviving into adulthood and
transferring from child to adult services has increased dramatically in the last 30 years. This …

Background: Disorders/differences of sex development (DSD) comprise a heterogeneous
group of inborn conditions where the individual's sex chromosomes, gonads, and/or …