Background Falls are a common cause of injury, hospitalization, functional decline, and
residential care admission among older adults. Cardiovascular disorders are recognized …

Down syndrome (DS) is the most common genetic cause of intellectual disability in children.
With aging, DS is associated with an increased risk for Alzheimer's disease (AD). The …

Introduction Many older people with orthostatic hypotension (OH) may not report typical
symptoms of dizziness, light-headedness or unsteadiness. However, the relationships …

Background Orthostatic hypotension (OH), cognitive impairment (Cog) and mobility
impairment (MI) frequently co-occur in older adults who fall. This study examines clustering …

In this Specialty Grand Challenge, we outline our vision of the current challenges in the field
of Network Physiology (Bashan et al., 2012; Bartsch et al., 2015; Ivanov et al., 2014) as …

Background The label 'faller'and the associated stigma may reduce healthcare-seeking
behaviours. However, falls are not inevitably progressive and many drivers are modifiable …

Background Previous evidence suggests that slower gait speed is longitudinally associated
with cognitive impairment, dementia and falls in older adults. Despite this, the longitudinal …

Background/Objectives There is growing interest in the association between gait
disturbance and depression in later life. The aim of this study is to clarify the longitudinal …

Objective Does baseline gait disturbance predict incident depression in a cohort of
community-dwelling older people? Methods This is a longitudinal study, embedded within …

BACKGROUND/OBJECTIVES Little work to date has examined the relationship between
gait performance and blood pressure (BP) recovery after standing in later life. The aim of this …