AMPK orchestrates an elaborate cascade protecting tissue from fibrosis and aging

S Jiang, T Li, Z Yang, W Yi, S Di, Y Sun, D Wang… - Ageing research …, 2017 - Elsevier
Fibrosis is a common process characterized by excessive extracellular matrix (ECM)
accumulation after inflammatory injury, which is also a crucial cause of aging. The process of …

[HTML][HTML] Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients

H Yanai, A Shteinberg, Z Porat, A Budovsky… - Aging (Albany …, 2015 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is an age-related fatal disease with unknown etiology and
no effective treatment. In this study, we show that primary cultures of fibroblasts derived from …

[HTML][HTML] Breath biomarkers in idiopathic pulmonary fibrosis: a systematic review

C Hayton, D Terrington, AM Wilson, N Chaudhuri… - Respiratory …, 2019 - Springer
Background Exhaled biomarkers may be related to disease processes in idiopathic
pulmonary fibrosis (IPF) however their clinical role remains unclear. We performed a …

MMP-7 is a predictive biomarker of disease progression in patients with idiopathic pulmonary fibrosis

Y Bauer, ES White, S de Bernard… - ERJ open …, 2017 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with poor
prognosis, which is characterised by destruction of normal lung architecture and excessive …

Protective effect of infliximab, a tumor necrosis factor-alfa inhibitor, on bleomycin-induced lung fibrosis in rats

N Altintas, M Erboga, C Aktas, B Bilir, M Aydin… - Inflammation, 2016 - Springer
We aimed to investigate the preventive effect of Infliximab (IFX), a tumor necrosis factor
(TNF)-α inhibitor, on bleomycin (BLC)-induced lung fibrosis in rats. Rats were assigned into …

[HTML][HTML] Increased cellular NAD+ level through NQO1 enzymatic action has protective effects on bleomycin-induced lung fibrosis in mice

GS Oh, SB Lee, A Karna, HJ Kim, AH Shen… - Tuberculosis and …, 2016 - ncbi.nlm.nih.gov
Background Idiopathic pulmonary fibrosis is a common interstitial lung disease; it is a
chronic, progressive, and fatal lung disease of unknown etiology. Over the last two decades …

[HTML][HTML] Membrane particles from mesenchymal stromal cells reduce the expression of fibrotic markers on pulmonary cells

A Merino, MJ Hoogduijn, M Molina-Molina… - Plos one, 2021 - journals.plos.org
Background Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with limited
treatment options in which the telomere shortening is a strong predictive factor of poor …

World health observances in September 2020: sepsis, the lung and heart, and pulmonary fibrosis in focus

C Nardiello, RE Morty - American Journal of Physiology …, 2020 - journals.physiology.org
Physiology. Sepsis, together with the lung and the heart are the focus of three separate
world health days: World Sepsis Day, World Lung Day, and World Heart Day (Fig. 1) …

The protection of glycyrrhetinic acid (GA) towards acetaminophen (APAP)-induced toxicity partially through fatty acids metabolic pathway

H Yang, T Jiang, P Li, Q Mao - African Health Sciences, 2015 - ajol.info
Background: Acetaminophen (APAP)-induced liver toxicity remains the key factor limiting the
clinical application of APAP, and herbs are the important sources for isolation of compounds …

Deregulation of microRNA Processing in Idiopathic Pulmonary Fibrosis

K Guenther - 2015 - conservancy.umn.edu
Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease with an incidence
in the United States of 42.7 to 63 per 100,000 and an incidence in Europe of 16.3 to 17.4 per …