[HTML][HTML] Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial
Background Tranexamic acid can prevent death due to bleeding after trauma and post-
partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma …
partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma …
[HTML][HTML] Luteolin Exerts Neuroprotection via Modulation of the p62/Keap1/Nrf2 Pathway in Intracerebral Hemorrhage
X Tan, Y Yang, J Xu, P Zhang, R Deng… - Frontiers in …, 2020 - frontiersin.org
Upregulation of neuronal oxidative stress is involved in the progression of secondary brain
injury (SBI) following intracerebral hemorrhage (ICH). In this study, we investigated the …
injury (SBI) following intracerebral hemorrhage (ICH). In this study, we investigated the …
[PDF][PDF] Fibroblasts repair blood-brain barrier damage and hemorrhagic brain injury via TIMP2
The function of fibroblasts in intracerebral hemorrhage (ICH) remains elusive. By targeting
Col1α1, a fibroblast-specific marker, we generate mice with ablated Col1α1+ fibroblasts …
Col1α1, a fibroblast-specific marker, we generate mice with ablated Col1α1+ fibroblasts …
[HTML][HTML] Stroke unit care, inpatient rehabilitation and early supported discharge
Stroke units reduce death and disability through the provision of specialist multidisciplinary
care for diagnosis, emergency treatments, normalisation of homeostasis, prevention of …
care for diagnosis, emergency treatments, normalisation of homeostasis, prevention of …
Managing high blood pressure during acute ischemic stroke and intracerebral hemorrhage
KO Appiah, JS Minhas… - Current Opinion in …, 2018 - journals.lww.com
There are clear national and international guidelines on BP lowering for specific indications,
as well as ongoing clinical trials aiming to address common clinical scenarios in which the …
as well as ongoing clinical trials aiming to address common clinical scenarios in which the …
[HTML][HTML] Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT.
N Sprigg, K Flaherty, JP Appleton… - Health Technology …, 2019 - ncbi.nlm.nih.gov
OBJECTIVE The aim of the study was to assess if tranexamic acid is safe, reduces
haematoma expansion and improves outcomes in adults with spontaneous intracerebral …
haematoma expansion and improves outcomes in adults with spontaneous intracerebral …
[HTML][HTML] Injectable collagen scaffold with human umbilical cord-derived mesenchymal stem cells promotes functional recovery in patients with spontaneous …
XY Li, WS Deng, ZQ Wang, ZC Li… - Neural Regeneration …, 2023 - journals.lww.com
Animal experiments have shown that injectable collagen scaffold with human umbilical cord-
derived mesenchymal stem cells can promote recovery from spinal cord injury. To …
derived mesenchymal stem cells can promote recovery from spinal cord injury. To …
Acute spontaneous intracerebral haemorrhage: treatment and management
S Mc Lernon, PS Nash… - British Journal of …, 2022 - magonlinelibrary.com
Acute spontaneous intracerebral haemorrhage is a devastating form of stroke, with high
rates of mortality and disability in survivors. Despite the burden of intracerebral …
rates of mortality and disability in survivors. Despite the burden of intracerebral …
Critical care transport of patients with brain injuries
R Zayas - AACN advanced critical care, 2018 - AACN
Critical care transport began in the 1970s as a response to the growing need to be able to
transport critically ill and injured patients to tertiary care centers for higher levels of care or …
transport critically ill and injured patients to tertiary care centers for higher levels of care or …
Interventional ultrasound assisted early local hemostatic drug therapy in traumatic intracerebral hemorrhage
C Feng, S Huang, X Zhou, L Wang, X Cui… - Ultrasound in Medicine …, 2020 - Elsevier
This article aims to test a minimally invasive interventional approach by real-time
transcranial contrast-enhanced ultrasound (CEUS) through a small bur hole to achieve an …
transcranial contrast-enhanced ultrasound (CEUS) through a small bur hole to achieve an …