Background An up-to-date overview of determinants of serum immunoglobulins in adults is
pivotal for clinical practice and research, but currently lacking. We therefore performed a …

Monoclonal gammopathy of undetermined significance (MGUS), precursor of multiple
myeloma, is an asymptomatic plasma cell disorder that overproduces serum monoclonal …

Summary This Good Practice Paper provides recommendations for the diagnosis, risk
stratification and management of the monoclonal gammopathy of undetermined significance …

Abstract Idiopathic Systemic Capillary Leak Syndrome (ISCLS), also known as Clarkson's
Syndrome, is due to primary fluid and protein leak across capillaries that leads to an …

OBJECTIVE Coexistence of polyneuropathy and gammopathy is a common but potentially
challenging situation in clinical practice. This article reviews the clinical, electrophysiologic …

Serum protein electrophoresis (SPEP) is a valuable laboratory test that separates proteins
from the blood based on their electrical charge and size. The test can detect and analyze …

Treatment advances have greatly improved survival, but myeloma is among the worst of all
cancers for delayed diagnosis, causing serious morbidities and early deaths. This delay is …

Monoclonal gammopathy of undetermined significance (MGUS) affects 3· 2% of adults
aged> 50 years. MGUS carries a life‐long risk of progression to multiple myeloma and …

Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell disorder
that can precede the diagnosis of multiple myeloma. MGUS is characterized by the presence …

Objective To systemically investigate the prevalence and risk factors of monoclonal
gammopathy (MG) in patients with autoimmune inflammatory rheumatic disease (AIIRD) …