Background Progress in characterising the humoral immune response to Severe Acute
Respiratory Syndrome 2 (SARS-CoV-2) has been rapid but areas of uncertainty persist …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing COVID-19 is
associated with excessive inflammation, as a main reason for severe condition and death …

The diagnosis of COVID‐19 requires integration of clinical and laboratory data. Severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) diagnostic assays play a central …

Figure 1 shows a schematic of the pattern of antibody response to SARS-CoV-2 infection.
Although immunoglobulin M (IgM) and immunoglobulin A (IgA) antibodies are widely …

Background COVID-19 has resulted in significant morbidity and mortality worldwide. Lateral
flow assays can detect anti-Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV …

Background: Since sensitivity and specificity vary widely between tests, SARS-CoV-2
serology results should be interpreted with caution. Methods: The study included serum …

Clinical laboratories across the world are working to validate and perform testing for SARS-
CoV-2 antibodies. Herein, we present interim consensus guidance for Canadian clinical …

We assessed the performance of the CoronaCHEK lateral flow assay on samples from
Uganda and Baltimore to determine the impact of geographic origin on assay performance …

Formulating accurate and robust classification strategies is a key challenge of developing
diagnostic and antibody tests. Methods that do not explicitly account for disease prevalence …

The COVID-19 pandemic has caused an unprecedented public health, social, and economic
crisis. Improving understanding on available tests for detecting COVID-19 is critical for …