[HTML][HTML] Acute-on-chronic liver failure: pathophysiological mechanisms and management

A Khanam, S Kottilil - Frontiers in medicine, 2021 - frontiersin.org
Acute-on-chronic liver failure (ACLF) is a multifaceted condition with poor treatment options
and high short-term mortality. ACLF can develop in patients with or without liver cirrhosis …

[PDF][PDF] Critical updates on chronic hepatitis B virus infection in 2021

CA Philips, R Ahamed, JK Abduljaleel, S Rajesh… - Cureus, 2021 - cureus.com
Chronic hepatitis B virus (HBV) infection is a global healthcare burden in the form of chronic
liver disease, cirrhosis, liver failure and liver cancer. There is no definite cure for the virus …

[HTML][HTML] Pathophysiology and management of liver cirrhosis: from portal hypertension to acute-on-chronic liver failure

RK Jagdish, A Roy, K Kumar, M Premkumar… - Frontiers in …, 2023 - frontiersin.org
Cirrhosis transcends various progressive stages from compensation to decompensation
driven by the severity of portal hypertension. The downstream effect of increasing portal …

[HTML][HTML] Vaccination in liver diseases and liver transplantation: recommendations, implications and opportunities in the post-Covid era

MP Ballester, R Jalan, G Mehta - JHEP Reports, 2023 - Elsevier
The interest in vaccination efficacy and toxicity has surged following the Covid-19 pandemic.
Immune responses to several vaccines have been shown to be suboptimal in patients with …

Regional citrate anticoagulation for continuous kidney replacement therapy with calcium-containing solutions: a cohort study

H Rhee, B Berenger, RL Mehta, E Macedo - American Journal of Kidney …, 2021 - Elsevier
Objective Regional citrate anticoagulation (RCA) is the preferred anticoagulation method for
continuous kidney replacement therapy (CKRT) recommended by KDIGO. Limited …

[HTML][HTML] Acute on chronic liver failure: prognostic models and artificial intelligence applications

PJ Gary, A Lal, DA Simonetto, O Gajic… - Hepatology …, 2023 - journals.lww.com
Critically ill patients presenting with acute on chronic liver failure (ACLF) represent a
particularly vulnerable population due to various considerations surrounding the syndrome …

[HTML][HTML] Mechanism and effect of HNF4α decrease in a rat model of cirrhosis and liver failure

M Melis, R Marino, J Tian, C Johnson, R Sethi… - Cellular and Molecular …, 2024 - Elsevier
Background & Aims HNF4α, a master regulator of liver development and the mature
hepatocyte phenotype, is down-regulated in chronic and inflammatory liver disease. We …

[HTML][HTML] Hepatic perfusion as a new predictor of prognosis and mortality in critical care patients with acute-on-chronic liver failure

J Vogg, C Maier-Stocker, S Munker, A Mehrl… - Frontiers in …, 2022 - frontiersin.org
Background & Aims: Liver diseases are frequent causes of morbidity and mortality
worldwide. Liver diseases can lead to cirrhosis, with the risk of acute-on-chronic liver failure …

[HTML][HTML] Current and future perspectives on acute-on-chronic liver failure: Challenges of transplantation, machine perfusion, and beyond

B Della Guardia, APCS Boteon… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Acute-on-chronic liver failure (ACLF) is a syndrome that occurs in patients with chronic liver
disease and is characterized by acute decompensation, organ failure and high short-term …

[HTML][HTML] Diabetes is associated with poor short-term prognosis in patients with hepatitis B virus-related acute-on-chronic liver failure

H Hu, X Hu, C Tian, Y Zhu, Y Liu, Q Cheng… - Hepatology …, 2021 - Springer
Background/purpose Associations between the disturbances in glucose homeostasis and
prognosis in patients with hepatitis B virus (HBV)-related acute-on-chronic liver failure …