Endothelial injury and microvascular/macrovascular thrombosis are common
pathophysiological features of coronavirus disease-2019 (COVID-19). However, the optimal …

The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the acute
respiratory syndrome-coronavirus-2 (SARS-CoV-2) poses a persistent threat to global public …

Heparin has been used extensively as an antithrombotic and anticoagulant for close to 100
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …

Plant polysaccharides represent a natural source material characterized by high ubiquity,
abundance and biological activities that can be utilised as organic matter in numerous …

Heparin, an old but first-line anticoagulant, has been used over a century. It is a
heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution …

Background and Purpose Currently, there are no licensed vaccines and limited antivirals for
the treatment of COVID‐19. Heparin (delivered systemically) is currently used to treat …

Background COVID-19 is a viral prothrombotic respiratory infection. Heparins exert
antithrombotic and anti-inflammatory effects, and might have antiviral properties. We aimed …

Heparan sulfate proteoglycans (HSPGs) encompass a group of glycoproteins composed of
unbranched negatively charged heparan sulfate (HS) chains covalently attached to a core …

Aims: Pharmacovigilance data are primarily used to identify adverse drug reactions by
screening for disproportionate reporting, ie more reports of certain combinations of adverse …

The remarkable and unique characteristics of polyglycerols (PG) have made them an
attractive candidate for many applications in the biomedical and pharmaceutical fields. The …