Mapping the complexities of Relative Energy Deficiency in Sport (REDs): development of a physiological model by a subgroup of the International Olympic Committee …

LM Burke, KE Ackerman, IA Heikura… - British Journal of …, 2023 - bjsm.bmj.com
The 2023 International Olympic Committee (IOC) consensus statement on Relative Energy
Deficiency in Sport (REDs) notes that exposure to low energy availability (LEA) exists on a …

Gastrointestinal bleeding in chronic kidney disease patients: a systematic review and meta-analysis

Y Lin, C Li, D Waters, CS Kwok - Renal Failure, 2023 - Taylor & Francis
Gastrointestinal bleeding (GIB) is a major cause of mortality in patients with renal failure. We
conducted a systematic review of the literature to evaluate the rates, predictors, and …

Repositioning of tubocurarine as analgesic and anti-inflammatory agent: exploring beyond myorelaxant activity

S Patel, J Shukla, S Jain, V Paliwal, N Tripathi… - Biochemical …, 2022 - Elsevier
Background and purpose Tubocurarine (d-TC), a non-depolarizing competitive blocker of
nicotinic acetylcholine receptors is extensively utilized for the relaxation of skeletal muscles …

First‐in‐human study of ONO‐4578, an antagonist of prostaglandin E2 receptor 4, alone and with nivolumab in solid tumors

S Iwasa, T Koyama, M Nishino, S Kondo… - Cancer …, 2023 - Wiley Online Library
EP4, a prostaglandin E2 receptor, has shown an immunosuppressive activity on cancer
cells. This first‐in‐human study evaluated ONO‐4578, a highly selective EP4 antagonist, as …

[HTML][HTML] Fixed-dose combination of NSAIDs and spasmolytic agents in the treatment of different types of pain—A practical review

M Janczura, M Kobus-Moryson, S Sip… - Journal of clinical …, 2021 - mdpi.com
This review presents the most common disease entities in which combinations of NSAIDs
and spasmolytic drugs are used to reduce pain. The benefits of fixed-dose combination …

Repurposing of digoxin in pain and inflammation: An evidence‐based study

S Patel, R Gururani, S Jain, N Tripathi… - Drug Development …, 2022 - Wiley Online Library
In recent years, the drug repositioning strategy has gained considerable attention in the drug
discovery process that involves establishing new therapeutic uses of already known drugs …

[PDF][PDF] Efficacy and safety of acupuncture for pregnancy-related low back pain: A systematic review and meta-analysis

R Li, L Chen, X Lin, R Zhen, Y Xu, J Huang, Y Ren - Heliyon, 2023 - cell.com
Background Pregnancy-related low back pain (PLBP) is a common musculoskeletal
disorder, affecting people's physical and psychological health. Acupuncture is widely used …

[HTML][HTML] Flavonoid-Rich Sambucus nigra Berry Extract Enhances Nrf2/HO-1 Signaling Pathway Activation and Exerts Antiulcerative Effects In Vivo

B Cicek, B Danısman, S Yildirim, N Yuce… - International Journal of …, 2023 - mdpi.com
Sambucus nigra (SN) berry extract is characterized by high antioxidant and anti-
inflammatory activity. The current study aimed to investigate the effect of SN berry extract …

[HTML][HTML] Treatment with non-steroidal anti-inflammatory drugs (NSAIDs) does not affect outcome in patients with acute myocarditis or myopericarditis

M Mirna, L Schmutzler, A Topf, E Boxhammer… - Journal of …, 2022 - mdpi.com
Background: Previous animal studies reported an association of non-steroidal anti-
inflammatory drugs (NSAIDs) with adverse outcomes in acute myocarditis, which is why …

[HTML][HTML] Screening of Anti-Inflammatory Activity and Metabolomics Analysis of Endophytic Fungal Extracts; Identification and Characterization of Perylenequinones …

R Spina, A Ropars, S Bouazzi, S Dadi, P Lemiere… - Molecules, 2023 - mdpi.com
Patients suffering from inflammatory chronic diseases are classically treated with anti-
inflammatory drugs but unfortunately are highly susceptible to becoming resistant to their …