Recent randomised controlled trials, such as ISCHEMIA and ORBITA, have overturned most
of what we were taught in medical school about hospital procedures considered necessary …

Treatment of stable coronary artery disease (CAD) relies on improved prognosis and relief of
symptoms. National and international guidelines on CAD support the indication of …

Ever since William Heberden's seminal description of angina pectoris in 1772, 1 attempts
have been made to find an effective treatment of this condition. Thomas Lauder Brunton was …

The goal of treatment in stable coronary artery disease is to improve prognosis and quality of
life of the patients. International Guidelines support revascularization procedures for …

Background Symptomatic relief is the primary goal of percutaneous coronary intervention
(PCI) in stable angina and is commonly observed clinically. However, there is no evidence …

There is strong evidence that percutaneous coronary interventions (PCI) reduce the risk of
myocardial infarction and death among patients with acute coronary syndromes. However …

Editor's note: This post is part of a Health Affairs Blog series titled “ORBITA: Lessons From A
Landmark Trial," which focuses on the recent study finding that coronary stenting did not …

Purpose of review Coronary artery disease remains the most common cause of death
worldwide. In patients with biomarker-positive acute coronary syndrome, the combination of …

Bangalore et al 1 concluded that routine revascularization is associated with greater
freedom from angina compared with optimal medical treatment (OMT). However, the greater …

Objective Randomised Blinded Investigation With Optimal Medical Therapy of Angioplasty in
Stable Angina (ORBITA) and coronary stents: A case study in the analysis and reporting of …