New oral agents for type 2 diabetes

AJ Krentz - Clinical Medicine, 2007 - ncbi.nlm.nih.gov
During the past half-century, oral antidiabetic drugs have played a major role in the
treatment of type 2 diabetes. First came the biguanides, ie phenformin, metformin and …

[HTML][HTML] Drugs for diabetes: part 4 acarbose

G Arungarinathan, GA McKay, M Fisher - Br J Cardiol, 2011 - bjcardio.co.uk
Acarbose is an alpha-glucosidase inhibitor acting in the gastrointestinal tract producing
modest reductions in postprandial hyperglycaemia, with negligible risk of hypoglycaemia …

A new era in type 2 diabetes mellitus treatment?

AMI Laws - The American Journal of Medicine, 2001 - amjmed.com
Until the results of the United Kingdom Prospective Diabetes Study (UKPDS) were
published in 1998, there was uncertainty about the best way to manage type 2 diabetes …

[PDF][PDF] Do we need new drugs for the treatment of type 2 diabetes mellitus?

G Vervoort, CJ Tack, KF Kok, P Wahab, RH Houwen… - Neth J. Med, 2007 - njmonline.nl
At this moment, approximately ten different classes of drugs are or soon will become
available for the treatment of type 2 diabetes mellitus (table 1). Of the glucoselowering …

Management of type 2 diabetes: defining the role of acarbose

JA Balfour, MI Wilde - Disease Management & Health Outcomes, 1997 - Springer
The chronic nature of type 2 (non-insulin-dependent) diabetes mellitus, and the importance
of monitoring and regulating blood glucose levels in order to minimise development of …

The PROTECT study: final results of a large multicenter postmarketing study in patients with type 2 diabetes

J Buse, K Hart, L Minasi, PROTECT Study Group - Clinical therapeutics, 1998 - Elsevier
The Precose® Resolution of Optimal Titration to Enhance Current Therapies (PROTECT)
trial was a nationwide postmarketing study designed to assess the effectiveness, tolerability …

A randomized double-blind trial of acarbose in type 2 diabetes shows improved glycemic control over 3 years (UK Prospective Diabetes Study 44)

RR Holman, CA Cull, RC Turner - Diabetes care, 1999 - Am Diabetes Assoc
OBJECTIVE: To determine the degree to which alpha-glucosidase inhibitors, with their
unique mode of action primarily reducing postprandial hyperglycemia, offer an additional …

[CITATION][C] Oral agents in type 2 diabetes: where to now?

LV Campbell, DJ Chisholm - Medical journal of Australia, 1999 - Wiley Online Library
Oral agents in type 2 diabetes: where to now? Page 1 research in palliative care comes easily -
an evidence-based model is not readily accommodated by clinical practice built around a more …

[CITATION][C] The evolving role of α‐glucosidase inhibitors

B Göke, C Herrmann‐Rinke - Diabetes/metabolism reviews, 1998 - Wiley Online Library
Acarbose, an-glucosidase inhibitor, is a drug for the treatment of adult diabetic patients in
combination with diet and with other oral anti-diabetic drugs or insulin. 1–3 Acarbose delays …

Oral antidiabetic drugs: their properties and recommended use

I Campbell - Prescriber, 2007 - Wiley Online Library
There are now five classes of oral anti‐diabetic drugs available, with metformin remaining
the cornerstone of drug therapy in type 2 diabetes. Our Drug review considers their mode of …