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Systemic AL amyloidosis has a poor prognosis which corresponds closely with the severity
of cardiac disease. 1, 2 Some patients benefit from chemotherapy directed at the underlying …

Prognosis is poor with a median survival of 4 months in patients presenting with heart
failure. 1 The echocardiograph often shows a thickened left ventricle with a granular …

Systemic AL amyloidosis hasa poor prognosis which corresponds closely with the severity of
cardiac disease.'2 Some patients benefit from chemotherapy directed at the underlying …

Cardiac involvement can be found in all types of amyloidosis, but is most frequent in AL
amyloidosis. Severity of cardiac infiltration is by far the most relevant prognostic determinant …

Amyloidosis is a systemic or organlimited disease in which there is extracellular deposition
of amyloid fibrils that gradually replace normal tissue in various organs in different …

Discussion Systemic amyloidosis generally results from widespread deposition of insoluble
fibrillar proteins, like free light chains with the heterogeneity of cardiac, renal or skin …

A 70-year-old Irish man presented with several months of breathlessness and lethargy,
which had become acutely worse over the preceding week. Exercise tolerance had …

Without therapy, the consequences of significant amyloid heart involvement are inevitably
fatal. Management requires a quick and exact determination of amyloid disease type as …

L amyloidosis is a multi-organ systemic disease and is usually rapidly fatal. The incidence of
A congestive heart failure (CHF) at the time of diagnosis of AL amyloidosis has been …