[HTML][HTML] The impact of false positive COVID-19 results in an area of low prevalence

B Healy, A Khan, H Metezai, I Blyth, H Asad - Clinical Medicine, 2021 - ncbi.nlm.nih.gov
False negative results in COVID-19 testing are well recognised and frequently discussed.
False positive results, while less common and less frequently discussed, still have several …

[HTML][HTML] False negative tests for SARS-CoV-2 infection—challenges and implications

S Woloshin, N Patel… - New England Journal of …, 2020 - Mass Medical Soc
False Negative Tests for SARS-CoV-2 Infection Diagnostic testing for SARS-CoV-2 will help
in safely reopening the country, but only if tests are highly accurate. Several steps need to …

[HTML][HTML] False negative rate of COVID-19 PCR testing: a discordant testing analysis

JN Kanji, N Zelyas, C MacDonald, K Pabbaraju… - Virology journal, 2021 - Springer
Background COVID-19 is diagnosed via detection of SARS-CoV-2 RNA using real time
reverse-transcriptase polymerase chain reaction (rtRT-PCR). Performance of many SARS …

COVID-19 testing: the threat of false-negative results

CP West, VM Montori… - Mayo clinic …, 2020 - mayoclinicproceedings.org
As health care systems around the world attempt to cope with the coronavirus disease 2019
(COVID-19)“tsunami,” concerns about ongoing spread of disease from individuals who are …

[HTML][HTML] Estimating the false-negative test probability of SARS-CoV-2 by RT-PCR

PS Wikramaratna, RS Paton, M Ghafari… - …, 2020 - eurosurveillance.org
Background Reverse-transcription PCR (RT-PCR) assays are used to test for infection with
the SARS-CoV-2 virus. RT-PCR tests are highly specific and the probability of false positives …

[HTML][HTML] False-negative results of initial RT-PCR assays for COVID-19: a systematic review

I Arevalo-Rodriguez, D Buitrago-Garcia… - PloS one, 2020 - journals.plos.org
Background A false-negative case of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection is defined as a person with suspected infection and an initial …

COVID-19 testing: impact of prevalence, sensitivity, and specificity on patient risk and cost

ZC Brooks, S Das - American Journal of Clinical Pathology, 2020 - academic.oup.com
Objectives To illustrate how patient risk and clinical costs are driven by false-positive and
false-negative results. Methods Molecular, antigen, and antibody testing are the mainstay to …

[HTML][HTML] Rethinking Covid-19 test sensitivity—a strategy for containment

MJ Mina, R Parker, DB Larremore - New England Journal of …, 2020 - Mass Medical Soc
Rethinking Covid-19 Test Sensitivity As Covid-19 cases accelerate or plateau around the
world, we urgently need a point-of-care test that is inexpensive enough to use frequently …

[HTML][HTML] Effectiveness of tests to detect the presence of SARS-CoV-2 virus, and antibodies to SARS-CoV-2, to inform COVID-19 diagnosis: a rapid systematic review

D Jarrom, L Elston, J Washington… - BMJ evidence-based …, 2022 - ebm.bmj.com
Objectives We undertook a rapid systematic review with the aim of identifying evidence that
could be used to answer the following research questions:(1) What is the clinical …

Risk factors for positive and negative COVID-19 tests: a cautious and in-depth analysis of UK biobank data

M Chadeau-Hyam, B Bodinier, J Elliott… - International journal …, 2020 - academic.oup.com
Background The recent COVID-19 outbreak has generated an unprecedented public health
crisis, with millions of infections and hundreds of thousands of deaths worldwide. Using …