Autoimmune haematological disorders
D Provan - Clinical Medicine, 2001 - ncbi.nlm.nih.gov
Fig 1. Loss of regulation of autoreactivity. The normal mechanisms controlling autoreactivity
are bypassed leading to T or B cell mediated autoimmune disease (reproduced, with …
are bypassed leading to T or B cell mediated autoimmune disease (reproduced, with …
Autoimmune Disorders: HLA, Genetic Predisposition, and the Immune System
TW Mak, JJL Simard - Handbook of Imune Response Genes, 1998 - Springer
Many diseases with autoaggressive immune components appear to have predisposing
genetic factors. Such a contention is supported by the observation of an increased …
genetic factors. Such a contention is supported by the observation of an increased …
Mechanisms and pathophysiology of autoimmune disease
WH Brooks - Clinical reviews in allergy & immunology, 2012 - Springer
The first textbook on autoimmunity was published by Ian Mackay and McFarland Burnett in
1963. It was the first attempt to summarize existing knowledge on human autoimmunity …
1963. It was the first attempt to summarize existing knowledge on human autoimmunity …
HLA association with autoimmune disease: a failure to protect?
E Zanelli, FC Breedveld, RRP De Vries - Rheumatology, 2000 - academic.oup.com
That certain HLA specificities are associated with predisposition to autoimmune disease
does not necessarily imply that self‐reactive T cells restricted to particular HLA alleles are …
does not necessarily imply that self‐reactive T cells restricted to particular HLA alleles are …
Autoimmune Chapter 21 hematological disorders
Autoimmune diseases are disorders where antibodies or cells react against self-antigens to
cause disease, at which point an adaptive immune response is mounted against the self …
cause disease, at which point an adaptive immune response is mounted against the self …
Autoimmune diseases
A Davidson, B Diamond - New England Journal of Medicine, 2001 - Mass Medical Soc
Autoimmune diseases, with the exception of rheumatoid arthritis and autoimmune thyroiditis,
are individually rare, but together they affect approximately 5 percent of the population in …
are individually rare, but together they affect approximately 5 percent of the population in …
Genetics of systemic autoimmunity
AN Theofilopoulos - Journal of autoimmunity, 1996 - Elsevier
Despite enormous efforts, the pathogenesis of lupus and other autoimmune diseases
remains unresolved, but recent studies in lupus mice have contributed several major …
remains unresolved, but recent studies in lupus mice have contributed several major …
Autoimmunity: experimental and clinical aspects
RS Schwartz, NR Rose - 1986 - osti.gov
This book contains five parts and a section of poster papers. Each part contains several
papers. Some of the papers are: Molecular Genetics and T Cells in Autoimmunity; Gene …
papers. Some of the papers are: Molecular Genetics and T Cells in Autoimmunity; Gene …
[HTML][HTML] Autoreactivity versus autoaggression: a different perspective on human autoantigens
SL Parry, FC Hall, J Olson, T Kamradt… - Current opinion in …, 1998 - Elsevier
Antigen-specific B and T cell responses against myelin basic protein, as well as responses
against β-islet-cells or joint tissue, are commonly found both in patients with autoimmune …
against β-islet-cells or joint tissue, are commonly found both in patients with autoimmune …
Mechanisms underlying autoimmunity in hematology
JW Semple, J Freedman - Drug Discovery Today: Disease Mechanisms, 2006 - Elsevier
Organ-specific autoimmune diseases are directed primarily at the autoantigens of particular
tissues, for example, platelets in autoimmune thrombocytopenic purpura (AITP) and …
tissues, for example, platelets in autoimmune thrombocytopenic purpura (AITP) and …