Aims This is a case report of a patient who presented with vague symptoms of headache,
arthralgia and lethargy that prompted the general practitioner (GP) to acquire thyroid …

Introduction Interference due to the presence of heterophilic antibodies may lead to falsely
low or high analyte concentrations, but falsely elevated values are more common in most …

Introduction: Interfering antibodies are capable of causing potentially misleading results in
automated thyroid hormone IMMUNOASSAY s. Case Presentation: We report the case of a …

Conclusion: Interference in immunoassays due to the presence of heterophilic antibodies
can result in falsely increased or decreased analyte concentrations including TSH. Analysis …

Thyroid-stimulating hormone (TSH) and thyroid hormone immunoassays are widely used in
clinical practice and play a major role in clinical decision-making. However, these assays …

Avoiding Misdiagnosis Due to Antibody Interference with Serum Free Thyroxin - PMC Back to
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Interference, for instance due to the presence of heterophilic antibodies, is a well-known
pitfall in diagnostic immunoassays. Although these antibodies were reported to be present in …

We report two patients who presented with non-specific symptoms of tiredness that
prompted their clinician to order a thyroid function test. In both cases, free thyroxine (T4) was …

We report two cases of euthyroid patients with inappropriately elevated serum levels of
thyrotropin (TSH) in whom investigation led to the detection of heterophilic antibodies. In …

Background: Endogenous and exogenous factors may cause biochemical interferences with
thyroid function immunoassays. Interference can be caused by many mechanisms including …