Editor–We read with interest the article by Bell and colleagues (Clin Med June 2009 pp 231–
5). They describe aciclovir therapy as essentially safe, highlighting the potential risk of …

Discussion Neurotoxicity can follow oral or intravenous administration of aciclovir, but is
usually associated with intravenous regimes. There is only one other reported case of coma …

Aciclovir is an anti-viral frequently used for herpes virus infections. Neurotoxicity and
nephrotoxicity are uncommon but serious side effects of aciclovir treatment. This case …

BACKGROUND Since its approval in 1982, acyclovir has been used frequently for the
prophylaxis and treatment of herpes simplex and varicella-zoster viral infections. Adverse …

Objectives: Neuropsychiatric symptoms related to aciclovir or valaciclovir treatment have
been a problem since aciclovir was introduced in the early 1980s. We have previously found …

Neurotoxicity can develop as a side effect of intravenous acyclovir use in patients with renal
impairment. It is underreported in clinical practice and often confused with worsening herpes …

Background. Acyclovir (ACV) has been used for over two decades to treat herpes virus
infections. Serious neurological adverse side effects have occurred during ACV treatment in …

[Encephalopathy and acute renal failure during acyclovir treatment]. - Abstract - Europe
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OBJECTIVE: To report a case of acute renal failureand neurotoxicity following administration
of oral acyclovir. DATA SOURCES: Medical record of the patient, case reports identified by …

Acyclovir is an antiviral drug frequently used in clinical practice. It is indicated for the
treatment of infections caused by herpes simplex virus and varicella zoster virus. The drug …