It is not possible to assess the prognosis of a patient in coma with complete accuracy but a
number of clinical factors that may be a guide include aetiology, depth and duration of coma …

One of the most difficult problems facing intensivists is understanding the natural history of
comatose patients and their possibility of recovery. One must consider, among many factors …

To the Editor: With therapeutic hypothermia becoming the standard of care after cardiac
arrest, more and more data are becoming available on the significance of different …

Coma is a state in which a patient is not responsive to external or internal stimuli. Early
assessment and aggressive management is essential for a good outcome. Neurological …

Background: The assessment of thalamocortical function in comatose patients in the
intensive care unit (ICU) can be difficult to determine. Since the electroencephalogram …

PREVIEW Coma is the most severe form of unresponsiveness, in which a patient is totally
unaware of self and surroundings. With the patient so disengaged during examination …

Coma is caused by temporary or permanent damage to the ascending reticular system or to
both cerebral hemispheres. It follows that the differential diagnosis of coma is wide …

Introduction Several studies have been performed to assess the prognostic value of early
neurological and neurophysiological findings in patients with postanoxic coma, but they …

Dear Sirs, Epidemiological data regarding the frequency of the different causes of coma and
their evolution over time in the ICU are scarce [1–4]. In the 1970s, Plum and Posner [2] …

Purpose: To determine the neurological clinical signs predicting poor outcome in patients
with coma of hypoxic/anoxic origin through a systematic review and critical appraisal of the …