Adult Paget's disease of bone is the second commonest metabolic bone condition after
osteoporosis. The condition is characterised by increased bone cell activity, with bone …

Adult PD of bone is the second commonest metabolic bone condition after osteoporosis. The
condition is characterized by increased bone cell activity, with bone-resorbing osteoclasts …

Paget's disease (PD) is a focal disorder of bone remodelling that occurs commonly in older
people. In this article, we review clinical aspects of PD with an emphasis on recent findings …

Genetic factors play an important role in the pathogenesis of Paget disease of bone (PDB).
SQSTM1 is the most important disease-associated gene identified to date. We investigated …

Paget's disease (PD) is a focal disorder of bone remodelling that occurs commonly in older
people. In this article, we review clinical aspects of PD with an emphasis on recent findings …

Paget's disease of bone (PDB) is the second most common metabolic bone disorder, after
osteoporosis. It is characterised by focal areas of increased and disorganised bone turnover …

OBJECTIVES: To review recent advance in understanding the causation and management
of Paget's disease. DESIGN AND METHODS: We review recent publications concerning the …

Paget's disease of bone (PDB) is a common chronic bone disorder. In the French-Canadian
population, the p. Pro392Leu mutation within the SQSTM1 gene is involved in 46% of …

Paget disease of bone (PDB) is a common disorder characterized by increased bone
turnover at one of more sites throughout the skeleton. Genetic factors play an important role …

Mutation screening of the SQSTM1 gene in 94 French patients with PDB revealed two novel
point‐mutations (A381V and L413F) and two new compound heterozygous genotypes …