[HTML][HTML] Diabetes remission: a realistic goal?

TA Chowdhury - Clinical Medicine, 2018 - ncbi.nlm.nih.gov
followed by a 4-week food reintroduction phase and a further weight maintenance phase up
to 2 years, using diet and exercise programmes to try to prevent weight regain. Mean weight …

[HTML][HTML] Diabetes Remission-The Holy Grail in Diabetes Management

S Mudaliar - Chronicle of Diabetes Research and Practice, 2024 - journals.lww.com
Chronicle of Diabetes Research and Practice¦ Volume 3¦ Issue 1¦ January‑June 2024 2 the
control group. The results of DiRECT confirm that T2DM is potentially reversible by weight …

Durability of a primary care-led weight-management intervention for remission of type 2 diabetes: 2-year results of the DiRECT open-label, cluster-randomised trial

MEJ Lean, WS Leslie, AC Barnes… - The lancet Diabetes & …, 2019 - thelancet.com
Summary Background The DiRECT trial assessed remission of type 2 diabetes during a
primary care-led weight-management programme. At 1 year, 68 (46%) of 149 intervention …

Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial

MEJ Lean, WS Leslie, AC Barnes, N Brosnahan… - The Lancet, 2018 - thelancet.com
Background Type 2 diabetes is a chronic disorder that requires lifelong treatment. We aimed
to assess whether intensive weight management within routine primary care would achieve …

[HTML][HTML] Clinical and metabolic features of the randomised controlled Diabetes Remission Clinical Trial (DiRECT) cohort

R Taylor, WS Leslie, AC Barnes, N Brosnahan, G Thom… - Diabetologia, 2018 - Springer
Aims/hypothesis Substantial weight loss in type 2 diabetes can achieve a return to non-
diabetic biochemical status, without the need for medication. The Diabetes Remission …

[HTML][HTML] What predicts drug-free type 2 diabetes remission? Insights from an 8-year general practice service evaluation of a lower carbohydrate diet with weight loss

D Unwin, C Delon, J Unwin, S Tobin… - … Nutrition, Prevention & …, 2023 - ncbi.nlm.nih.gov
Background Type 2 diabetes (T2D) is often regarded as a progressive, lifelong disease
requiring an increasing number of drugs. Sustained remission of T2D is now well …

[CITATION][C] Extension study from DIRECT showed ongoing remission rate from type 2 diabetes in some patient following very low calorie diet at 5 years

I Idris - 2024 - Wiley Online Library
Previous experimental study have shown that very low calorie Diet (VLCD) 1 can induced
remission from type 2 diabetes by reduction in fat contents in the pancreas and in the liver …

[HTML][HTML] 5-year follow-up of the randomised Diabetes Remission Clinical Trial (DiRECT) of continued support for weight loss maintenance in the UK: an extension …

MEJ Lean, WS Leslie, AC Barnes… - The Lancet Diabetes & …, 2024 - thelancet.com
Summary Background In DiRECT, a randomised controlled effectiveness trial, weight
management intervention after 2 years resulted in mean weight loss of 7· 6 kg, with 36% of …

[HTML][HTML] Translation of a Diabetes Remission Service into Australian Primary Care: Findings from the Evaluation of DiRECT-Australia

R Chimoriya, K Mitlehner, CL Khoo… - Journal of Diabetes …, 2024 - hindawi.com
Background. The Diabetes Remission Clinical Trial (DiRECT) study demonstrated that an
intensive and structured weight management program in UK primary care resulted in high …

Prevention and reversal of type 2 diabetes: highlights from a symposium at the 2019 Diabetes UK annual professional conference

R Taylor, J Valabhji, P Aveyard, D Paul - Diabetic Medicine, 2019 - Wiley Online Library
Aim This symposium covers the gamut of Type 2 diabetes prevention, reversing established
Type 2 diabetes, population‐level delivery of weight loss programmes and personal insights …