Controversies in revascularisation for stable coronary artery disease
Alexandra N Nowbar, Christopher Rajkumar, Rasha K Al-Lamee and Darrel P Francis
DOI: https://doi.org/10.7861/clinmed.2020-0922
Clin Med March 2021 Alexandra N Nowbar
ANational Heart and Lung Institute, London, UK and Hammersmith Hospital, London, UK
Roles: clinical research fellow
Christopher Rajkumar
ANational Heart and Lung Institute, London, UK and Hammersmith Hospital, London, UK
Roles: clinical research fellow
Rasha K Al-Lamee
BNational Heart and Lung Institute, London, UK and Hammersmith Hospital, London, UK
Roles: clinical senior lecturer
Darrel P Francis
CNational Heart and Lung Institute, London, UK and Hammersmith Hospital, London, UK
Roles: professor of cardiology
Article Information
vol. 21 no. 2 114-118
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History:
- Published online March 24, 2021.
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© Royal College of Physicians 2021. All rights reserved.
Author Information
- Alexandra N Nowbar, clinical research fellowA⇑,
- Christopher Rajkumar, clinical research fellowA,
- Rasha K Al-Lamee, clinical senior lecturerB and
- Darrel P Francis, professor of cardiologyC
- ANational Heart and Lung Institute, London, UK and Hammersmith Hospital, London, UK
- BNational Heart and Lung Institute, London, UK and Hammersmith Hospital, London, UK
- CNational Heart and Lung Institute, London, UK and Hammersmith Hospital, London, UK
- Address for correspondence: Dr Alexandra N Nowbar, B block South, 2nd floor, National Heart and Lung Institute – Cardiovascular Science, Du Cane Road, London W12 0NN, UK. Email: alexandra.nowbar09{at}imperial.ac.uk Twitter: @AlexNowbar, @rajkumar_chris, @rallamee, @ProfDFrancis
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Controversies in revascularisation for stable coronary artery disease
Alexandra N Nowbar, Christopher Rajkumar, Rasha K Al-Lamee, Darrel P Francis
Clinical Medicine Mar 2021, 21 (2) 114-118; DOI: 10.7861/clinmed.2020-0922
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- ABSTRACT
- Coronary artery disease
- Each extra vessel of coronary disease doubles mortality
- Ischaemia as a proxy for coronary disease
- Invasive ischaemia as an immediate catheter laboratory proxy for non-invasive ischaemia
- Unimpeachable evidence of therapeutic benefit from placebo-controlled trials
- Testing whether ischaemia ‘causes’ rather than ‘is associated with’ mortality
- Patients still often assume that elective revascularisation is life-saving
- Testing whether revascularisation relieves symptoms
- Left main stem disease
- Summary
- Key points
- Conflicts of interest
- References
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