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End-tidal carbon dioxide as a screening tool in excluding pulmonary embolism

Badie Jacob, Imad Riaz, Laura Batey and Henna Anwar
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DOI: https://doi.org/10.7861/clinmed.Let.22.5.1
Clin Med September 2022
Badie Jacob
Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
Roles: Consultant respiratory physician
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Imad Riaz
Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
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Laura Batey
Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
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Henna Anwar
Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK
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    Fig 1.

    Computed tomography pulmonary angiography (CTPA) positive and CTPA negative results for end-tidal carbon dioxide (ETCO2). The red line represents threshold of 4.3 kPa (32.3 mmHg). This figure shows that no patient with a ETCO2 of >4.3 kPa had a pulmonary embolism. PE = pulmonary embolism.

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    Fig 2.

    Area under receiver operator characteristic curves (AUROCCs) for the true positive rate against the false positive rate for different possible cut-off points. a) Wells score, AUROCC = 0.5891. b) D-dimer, AUROCC = 0.8468. c) End-tidal carbon dioxide, AUROCC = 0.8768.

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    Table 1.

    End-tidal carbon dioxide classification table over a range of cut-off thresholds

    ETCO2, kPaSensitivity, %Specificity, %Positive predictive value, %Negative predictive value, %
    10100065
    21982565
    360897581
    487756692
    4.399656099
    51002542100
    6100937100
    • ETCO2 = end-tidal carbon dioxide.

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End-tidal carbon dioxide as a screening tool in excluding pulmonary embolism
Badie Jacob, Imad Riaz, Laura Batey, Henna Anwar
Clinical Medicine Sep 2022, 22 (5) 496-497; DOI: 10.7861/clinmed.Let.22.5.1

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End-tidal carbon dioxide as a screening tool in excluding pulmonary embolism
Badie Jacob, Imad Riaz, Laura Batey, Henna Anwar
Clinical Medicine Sep 2022, 22 (5) 496-497; DOI: 10.7861/clinmed.Let.22.5.1
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